Antivenins act by neutralizing the venoms (complex proteins) in patients via passive immunization of globulins obtained from horses immunized with the venom. Antivenin is very effective in reversing venom-related coagulation abnormalities, but Timber Rattlesnake venom-induced thrombocytopenia may be resistant to treatment.
This product is indicated for the treatment of envenomation from the Eastern coral snake ( _Micrurus fulvius fulvius_ ) and the Texas coral snake ( _Micrurus fulvius tenere_ ). It will not neutralize the venom form the Sonoran or Arizona coral snake ( _Micruroides euryxanthus_ ) or the Brazilian giant coral snake ( _Micrurus frontalis_ ). Coral snake envenomation is quite rare in the United States and approximately 60% of coral snake bites do not result in envenomation. Unlike pit viper venom, coral snake venom primarily causes neurotoxicity and clinical signs may be delayed. It has been recommended that animals suspected of a coral snake envenomation be hospitalized with close observation for 24 – 48 hours post-bite.
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
D0750 的確切 Pfizer/Wyeth 產品是美國人用凍乾馬源珊瑚蛇抗毒血清,不是 D0748 歷史 Crotalidae 馬源全 IgG、D0749 CroFab 羊源 Fab、ANAVIP 馬源 F(ab')2,也不是 2024 犬貓研究的 Costa Rica 液態 Anti-Coral/CoRal-ICP。現有資料把這些產品、pit-viper 凝血機轉、犬貓馬瓶數與 IM 途徑混在一起;在逐一核對具名產品、批號效期、蛇種、病患物種、途徑、許可與 ICU 能力前,不得計算或生成處方。
DRUGAPI 劑量審查引用的獸醫官方標示(各標示只適用於其產品、物種與法域,不可互換)
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。