Aztreonam is a bactericidal antibiotic that binds to penicillin-binding protein-3 thereby inhibiting bacterial cell wall synthesis resulting in cell lyses and death of susceptible bacteria. Aztreonam is relatively stable to the effects of bacterial beta-lactamases and unlike many other beta-lactam antibiotics, it does not induce the activity of beta-lactamases. Aztreonam has activity against many species and most strains of the following gram-negative bacteria: _Aeromonas_, _Citrobacter_, _Enterobacter_, _E. coli_, _Klebsiella_, _Pasturella_, _Proteus, Pseudomonas_ and _Serratia_ . It is not clinically efficacious against gram-positive or anaerobic bacteria. Aztreonam can be synergistic against _Pseudomonas aeruginosa_ and other gram-negative bacilli when used with aminoglycosides.
Baclofen may be useful to decrease urethral resistance in dogs to treat urinary retention. It is not recommended for cats.
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
公開獸醫證據只支持犬的單次實驗藥動學／處置觀察，以及一篇只有書目、無公開摘要數值的駒馬靜脈藥動學研究；沒有可閉合犬、貓或魚類臨床療程的公開免費證據。現有犬 30 mg/kg 每 6–8 小時是人類兒科標示外推，錦鯉固定療程未由已開啟來源確認，貓口服劑量則是明顯無來源污染。注射用 Aztreonam、吸入型 CAYSTON 與 aztreonam/avibactam 複方不是可互換產品。未核對確切人用產品／製劑、動物物種、感染部位、培養藥敏、給藥途徑、腎肝功能、併用抗菌藥、法域與食用動物殘留前，不得自動計算、開立或向飼主顯示劑量。
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。