Dexrazoxane is hydrolyzed to an active metabolite that chelates intracellular iron that is believed to prevent the formation of an anthracycline-iron complex thought to be the primary cause of anthracycline-induced cardiomyopathy.
Dextran 70 is a relatively low cost colloid for the adjunctive treatment of hypovolemic shock. Hetastarch is the more commonly employed synthetic colloid used today.
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
現行 standard 劑量是歷史人體 1000/1000/500 mg/m² 外滲方案誤映射。犬合併治療與外滲資料方案異質,貓證據極少;人用、犬研究、病例方案不可互換。只有院內腫瘤/急診危害性藥物流程可個案決定。
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。