商品名：DMSO and Domoso
DMSO is a solvent that is a byproduct of the paper-making process. It is highly hygroscopic (water absorbing). It readily displaces water and will penetrate cell membranes, skin, and mucosa easily. It produces anti-inflammatory, antifungal, and antibacterial properties. The clinical anti-inflammatory action of DMSO is uncertain. It may produce anti-inflammatory or protective effects on cell membranes via its ability to scavenge oxygen-derived free radicals. In horses, at a dose of 1 g/kg, the half-life is 8.6 hours. Twenty-six percent of the administered dose was excreted in the urine. In dogs, the half-life is 36 hours.
DMSO is administered topically and systemically (IV) for treatment of various inflammatory conditions. It is popular in horses for treatment of laminitis, arthritis, pneumonia, intestinal ischemia, synovitis, and nervous system injuries. Despite popular use, there are no published reports of efficacy for clinical use, and evidence to support use as an anti-inflammatory agent in treatment of clinical disease is primarily anecdotal. There is no evidence to support use to protect ischemic reperfusion injury in the equine intestine, to treat laminitis, or to improve neurologic disease. It does not promote drug penetration across the blood–brain barrier. 240 Dimethyl Sulfoxide (DMSO) Instructions for Use Dilute prior to use to 10% for intravenous infusion. Doses vary widely among veterinarians.
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
單方 solution、gel、耳用複方與任何無菌全身製劑不可互換；使用前需確認產品、濃度、物種、適應症、途徑、部位清潔／污染、療程、繁殖／食用／競賽身分與監測。
DRUGAPI 劑量審查引用的獸醫官方標示（各標示只適用於其產品、物種與法域，不可互換）
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。