商品名:Dopram, Respiram
Respiratory stimulation of doxapram results from direct stimulation of the medullary respiratory center and activation of the aortic and carotid body chemoreceptors to improve sensitivity to carbon dioxide. These receptors are sensitive to changes in CO2, which in turn stimulate the respiratory center. Doxapram is used primarily in emergency during anesthesia or to decrease the respiratory depressant effects of certain drugs (e.g., opiates, barbiturates). An important use in veterinary medicine is stimulation of respiration in young horses. The half-life is short (2 hours), but the duration of
Doxapram may stimulation respiration in dogs, cats, and horses, during and after general anesthesia. It has been used to stimulate respiration on newborn animals following dystocia or cesarean section surgery. Doxapram will increase ventilation (tidal volume, respiratory rate) and reduce acidosis. In horses, doxapram will cause cardiac stimulation and respiratory stimulation. There have been reports that administration to neonates may increase their suckling activity shortly after birth and subsequently decrease the incidence of failure of passive transfer of immunoglobulins. The primary use o
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
Doxapram 是短效急救/麻醉/程序刺激劑,不是通用劑量。必須確認產品、濃度、防腐劑、法規、物種、適應症、麻醉時點、氣道與 PPV、ECG/BP/CO2/CNS 監測及急救準備;新生犬貓例行使用明確不建議。
DRUGAPI 劑量審查引用的獸醫官方標示(各標示只適用於其產品、物種與法域,不可互換)
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。