商品名:Epirubicin*, Pharmorubicin*
Intracellularly its metabolism results in production of cytotoxic free radicals. It also binds irreversibly to DNA, thereby preventing replication. It also alters membrane functions.
Cytotoxic anthracycline glycoside antibiotic that has demonstrated efficacy against several human neoplasms. In the dog the drug has been assessed against lymphoma (similar efficacy to doxorubicin) and also as an adjunct in the management of splenic haemangiosarcoma. It may be used alone or in combination with other antineoplastic therapies. The drug must be given i.v. Premedication with i.v. chlorphenamine or dexamethasone is recommended. As extravasation of the drug is likely to result in seve
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
表柔比星是療程綁定的細胞毒化療藥;研究數字不能脫離腫瘤診斷、體表面積、療程、器官功能、血球與累積蒽環類曝露自動計算。supported_species 只代表有犬貓文獻,不代表可直接開立。
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。