商品名:Robinul*
Blocks the action of acetylcholine at muscarinic receptors at the terminal ends of the parasympathetic nervous system, reversing parasympathetic effects. Its quaternary structure prevents it from crossing the blood-brain barrier and so it is devoid of central effects.
Potent antisialagogue agent and has been used preoperatively to decrease oral and bronchial secretions. It is also used to inhibit vagal efferent activity and manage bradycardias caused by the administration of potent opioid drugs. Glycopyrronium is used with long-acting anticholinesterase drugs (e.g. neostigmine, pyridostigmine) during antagonism of neuromuscular block. Glycopyrronium is longer acting than atropine. Routine administration of glycopyrronium prior to anaesthesia as part of premed
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
Glycopyrronium 與 glycopyrrolate 是同義命名,資料庫仍有重複身分待人工合併;美國與法國產品的鹽型、貓途徑與標示並不相同。馬僅有小型 IV 麻醉救援研究且有腸停滯風險,故通用計算與飼主劑量封鎖。
DRUGAPI 劑量審查引用的獸醫官方標示(各標示只適用於其產品、物種與法域,不可互換)
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。