Leuprolide is a luteinizing hormone-releasing hormone agonist. Via negative feedback, leuprolide inhibits the release of luteinizing hormone and follicle stimulating hormone from the pituitary. Both estrogen and androgen levels are decreased in the serum.
Depending on the product licensed, levamisole is indicated for the treatment of many nematodes in cattle, sheep and goats, swine, poultry. In sheep and cattle, levamisole has relatively good activity against abomasal nematodes, small intestinal nematodes (not particularly good against _Strongyloides_ spp.), large intestinal nematodes (not _Trichuris_ spp.), and lungworms. Adult forms of species that are usually covered by levamisole, include: _Haemonchus_ spp., _Trichostrongylus_ spp., _Osteragia_ spp., _Cooperia_ spp., _Nematodirus_ spp., _Bunostomum_ spp., _Oesophagostomum_ spp., _Chabertia_ spp., and _Dictyocaulus_ _vivapurus_ . Levamisole is less effective against the immature forms of these parasites, and is generally ineffective in cattle (but not sheep) against arrested larval forms. Resistance of parasites to levamisole is a growing concern. In swine, levamisole is indicated for the treatment of _Ascaris_ _suum_, _Oesophagostomum_ spp. _,_ Strongyloides _,_ Stephanurus, and Metastrongylus _._ Levamisole has been used in dogs as a microfilaricide to treat _Dirofilaria immitis_ infection in the past, but is rarely used today. It has also garnered some interest as an immunostimulant in the adjunctive therapy of various neoplasms. Because of its narrow margin for safety and limited efficacy against many equine parasites, levamisole is not generally used in horses as an antiparasitic agent. It has been tried as an immune stimulant, however.
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
確認精確化學實體與鹽型 確認精確產品、濃度與遞送系統 確認物種、性別、診斷與生殖狀態 由主治獸醫師制定個別化施作、監測、重複與停止規則
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。