商品名:Cytopoint (Zoetis)
Lokivetmab is a caninized monoclonal antibody that specifically targets and neutralizes canine interleukin-31 (IL-31). IL-31 is a key pruritogenic cytokine found at elevated levels in dogs with atopic dermatitis. By binding IL-31, lokivetmab prevents its interaction with the IL-31RA/OSMRβ receptor complex on sensory neurons, blocking itch signaling.
Treatment of atopic dermatitis and allergic dermatitis in dogs. USDA-approved December 2016; extended label 2018 for allergic dermatitis.
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
runtime 無法同時閉合精確 Cytopoint 產品、法域、犬限定適應症、目前體重、小瓶表、皮下途徑、年齡/生殖/過敏狀態、感染評估、反應/免疫原性、疫苗/其他單株抗體/合併用藥、施打人員與監測。美國與英國/歐盟的劑量與間隔規則不得合併。30 張數值卡全都只能供查閱。
DRUGAPI 劑量審查引用的獸醫官方標示(各標示只適用於其產品、物種與法域,不可互換)
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。