商品名:Aredia*, Pamidronate*
Inhibits osteoclast activity and induces osteoclast apoptosis.
Treatment of hypercalcaemia (especially associated with vitamin D toxicosis and hypercalcaemia of malignancy, or if other therapeutic regimens are unsuccessful). In human medicine it is also used to treat osteolytic lesions and bone pain due to bone metastases associated with breast cancer, multiple myeloma and Paget’s disease. There may be clinical usefulness in directly treating ‘micrometastases’ in osteosarcomas but studies are ongoing.
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
D0505 與 D0506 描述相同臨床胰酶實體,但產品效價、單位系統、釋放型態與標籤狀態不同;任何合併茶匙、錠數或膠囊換算皆不安全。
DRUGAPI 劑量審查引用的獸醫官方標示(各標示只適用於其產品、物種與法域,不可互換)
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。