商品名:Inderal and generic brands
Beta-adrenergic blocker. Nonselective for beta1- and beta2-adrenergic receptors. Class II antiarrhythmic. Propranolol is a lipophilic beta blocker and relies on the liver for clearance. Lipophilic beta blockers such as propranolol undergo high first-pass clearance, which reduces oral bioavailability and causes high interpatient variability in plasma concentrations and effects. Drug concentrations may be higher when there is impaired liver blood flow.
Propranolol is used primarily to decrease heart rate, decrease cardiac conduction, control tachyarrhythmias, and decrease blood pressure. Propranolol is effective in controlling the response from adrenergic stimulation. Beta blockers such as propranolol are among the most effective drugs for slowing heart rate. Propranolol Hydrochloride 661 P Instructions for Use Usually dose is titrated according to patient’s response. Start with low dose and increase gradually to desired effect. Clearance relies on hepatic blood flow; use cautiously in animals with impaired hepatic perfusion. In cats with hy
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
目前犬貓數字與用途、route、產品及證據不一致;在心律診斷、ECG、產品釋放型態、鹽重/base、心肺狀態、血糖風險與監測全部確認前,禁止產生 mg/mL。
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。