商品名:Veklury (Gilead) / compounded
Remdesivir is a nucleotide analogue prodrug. It is metabolized intracellularly to its active form (GS-443902), which acts as an ATP analogue that inhibits RNA-dependent RNA polymerase (RdRp) of coronaviruses. In cats, it is used for its activity against feline coronavirus causing FIP. Remdesivir is converted in vivo to GS-441524, which is also directly used as an antiviral for FIP.
Treatment of feline infectious peritonitis (FIP). Used as injectable form; GS-441524 (the metabolite) is also available in oral form. Major breakthrough in FIP treatment.
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。