商品名:Rapamune, felycin
Macrolide that binds FKBP12 and inhibits mTOR (mechanistic target of rapamycin), blocking T-cell proliferation at G1-S transition. Also inhibits angiogenesis and has anti-tumor properties. Unlike calcineurin inhibitors, does not inhibit calcineurin.
Investigational in veterinary medicine: immune-mediated diseases, organ transplant rejection prevention, adjunct anti-cancer therapy (anti-angiogenic)
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
DRUGAPI 劑量審查引用的獸醫官方標示(各標示只適用於其產品、物種與法域,不可互換)
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。