商品名:Actigall, Ursodeoxycholic acid, Urso
Hydrophilic bile acid. Anticholelithic and choleretic. Ursodiol is the short name for ursodeoxycholic acid. This is a naturally occurring, water-soluble bile acid. Ursodiol, like other bile acids, can act as a choleretic and increase bile flow. In dogs, it may alter pool of circulating bile acids, displacing the more hydrophobic bile acids or enhancing their secretion in liver and bile. By modulating the composition of biliary bile salts in favor of more hydrophilic bile salts, injury to the biliary epithelium, such as the cytotoxic potential of endogenous bile acids, is less likely than with
Ursodiol is used for treatment of liver diseases. It is used to treat primary biliary cirrhosis, cholestatic liver disorders, and chronic liver disease. Although experimental evidence exists for its benefit in dogs, there are no well-controlled clinical trials that demonstrate efficacy. In people it has been used as a laxative and to prevent or treat gallstones.
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
必須確認精確活性本體、成品或調劑品、劑型、強度或濃度、動物別、診斷、膽道通暢性與所在地現行法規。 慢性肝炎、膽汁淤積、膽囊黏液囊腫、膽管炎、膽結石、膽道阻塞及單純肝酵素升高不得互換。 犬與貓的研究、健康動物與患病動物、人用標示與獸醫情境均不得互相轉移。
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。
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