商品名:Zovirax and generic brands
Antiviral drug. Acyclovir is a synthetic purine analogue (acyclic nucleoside analogue). It has antiviral activity against herpes virus. The action is related to the affinity for the enzyme thymidine kinase (TK). However, resistance among some virus forms is possible because of changes in TK or in the DNA polymerase. It is used for treatment of various forms of herpes virus infection in humans and also has been used for treatment of viral infections in animals. However, feline herpes virus 1 (FHV1) is resistant to acyclovir and valciclovir, and studies are lacking on the susceptibility of other
Acyclovir is an antiviral drug. The use in veterinary medicine is limited because the activity against some viruses (e.g., FHV1) is either poor or unknown. In cats, acyclovir had poor absorption and produced toxicity. Acyclovir is able to inhibit replication of equine herpes virus (EHV1) in vitro. However, acyclovir oral absorption in horses was poor and inconsistent and intravenous treatment is needed for treatment of EHV1 infection.
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
由獸醫師先解析 D0019 與 D0021 的同成分重複身分,再確認精確活性成分、鹽型、產品與法域。 確認物種、病毒與病灶、診斷證據、嚴重度、免疫狀態及替代方案。 確認腎臟與水合狀態、神經與血液風險、所有同時用藥、眼用無菌及調劑品質。 建立個案監測、反應、停止、失敗與緊急救援計畫。
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。
fecal