商品名:Famvir
Antiviral drug. Famciclovir is a synthetic purine analogue (acyclic nucleoside analogue). It is converted to the antiviral drug penciclovir and has antiviral activity against herpes virus type 1 and 2. The action is related to the affinity for the enzyme thymidine kinase (TK), which converts penciclovir into penciclovir triphosphate, which inhibits viral DNA polymerase to prevent DNA chain elongation—thus inhibiting viral DNA chain elongation. It is used for treatment of various forms of herpes virus infection in humans and also has been used for treatment of viral infections in animals. Howev
Although in vitro testing does not indicate high activity against the virus, famciclovir has been used to treat feline herpes virus (FHV1) associated with conjunctivitis, rhinosinusitis, keratitis, and FHV1-associated dermatitis. In treated cats there was improvement of conjunctivitis, decreased conjunctival inflammation, decreased ocular discomfort, and decreased tearing.
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
確認成分是泛昔洛韋而非噴昔洛韋或其他抗病毒藥,並核對成品、劑型、濃度、來源與配製資訊 確認物種、體重、年齡、妊娠或哺乳狀態、腎肝功能、水合狀態、血液學風險與完整共用藥 確認病毒、診斷方法、感染或再活化狀態、急性或慢性疾病、眼部或呼吸道或皮膚表現及嚴重度 依精確研究情境選擇方案,不得平均或拼接實驗感染、自然疾病、收容所、預防性與藥動學研究數字 建立臨床與病毒學反應、實驗室追蹤、失敗判定、停藥門檻、不良反應與救援計畫
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。