商品名：Geopen and Pyopen Carbenicillin indanyl sodium
Beta-lactam antibiotic. Carbenicillin has an action similar to ampicillin, which inhibits bacterial cell wall synthesis. Carbenicillin has a broad spectrum of activity that includes both gram-positive and gram-negative bacteria. However, resistance is possible, especially among beta-lactamase–positive strains. The difference between carbenicillin and ampicillin is that it is active against Pseudomonas aeruginosa and other gram- negative bacteria that are resistant to ampicillin and amoxicillin. Half-life is short and clearance is rapid in animals; therefore it requires frequent administration.
Carbenicillin is used to treat gram-negative infections in animals, including infections caused by Pseudomonas aeruginosa. The use of carbenicillin is uncommon in veterinary medicine and has been replaced by other drugs such as ticarcillin and cephalosporins. Indanyl sodium carbenicillin (Geocillin) is poorly absorbed orally and should not be used for systemic infections. However, this form may produce high enough urine concentrations for treating some infections of lower urinary tract. Instructions for Use Carbenicillin has a short half-life and should be administered frequently for optimum bactericidal effect. Carbenicillin injection often is administered with an aminoglycoside when treating Pseudomonas infections. Do not mix with aminoglycosides prior to administration or inactivation w
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
公開資料混合歷史 oral indanyl、parenteral disodium 與未註明鹽型的衝突範圍；現行犬貓 UTI 指南未建立 carbenicillin regimen。確認 exact product／salt、感染部位、培養 MIC、腎功能、尿量、水合、sodium／fluid／bleeding 風險與監測前，封鎖通用計算、處方及飼主劑量。
DRUGAPI 劑量審查引用的獸醫官方標示（各標示只適用於其產品、物種與法域，不可互換）
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。
renal