Although not a true cephalosporin, cefoxitin is usually classified as a 2nd generation agent. Cefoxitin has activity against gram-positive cocci, but less so on a per weight basis than the 1st generation agents. Unlike the first generation agents, it has good activity against many strains of _E. coli,_ Klebsiella and Proteus that may be resistant to the first generation agents. In human medicine, cefoxitin’s activity against many strains of _Bacteroides_ _fragilis_ has placed it in a significant therapeutic role. While _Bacteroides_ _fragilis_ has been isolated from anaerobic infections in veterinary patients, it may not be as significant a pathogen in veterinary species as in humans. Because 2nd generation cephalosporins exhibit specific activities against bacteria, a 30-microgram cefoxitin disk should be used when performing Kirby-Bauer disk susceptibility tests for this antibiotic.
In dogs, cefpodoxime is indicated for the treatment of skin infections caused by _Staphylococcus intermedius, Staphylococcus aureus,_ _Streptococcus canis, E. coli, Proteus mirabilis,_ and _Pasteurella multo-_ _cida_ . Although not currently approved for cats, it may also be useful as well.
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。