Ceftriaxone is a third generation injectable cephalosporin agent. The third generation cephalosporins retain the gram-positive activity of the first and second-generation agents, but, have much expanded gram-negative activity. As with the 2nd generation agents, enough variability exists with individual bacterial sensitivities that suscepti bility testing is necessary for most bacteria. Because of the excellent gram-negative coverage of these agents and when compared to the aminoglycosides and their significantly less toxic potential, they have been used on an increasing basis in veterinary medicine.
Cefuroxime is a semi-synthetic 2nd generation cephalosporin with enhanced activity against some gram-negative pathogens when compared to the first generation agents. Cefuroxime is available in both oral and parenteral dosage forms. It potentially may be useful in small animals when a cephalosporin is desired to treat bacterial infections susceptible to cefuroxime, but resistant to first generation cephalosporins, when enhanced gram-negative coverage is desired for surgery prophylaxis, or when high CNS levels are necessary. Little information is available with regard to its clinical use in small animals, however.
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。