商品名:Zyrtec
Antihistamine (H1-blocker). Cetirizine is the active metabolite of hydroxyzine. Almost all hydroxyzine in dogs is converted to cetirizine. Cetirizine is similar to other antihistamines—it acts by blocking the histamine type-1 (H1) receptor and suppressing inflammatory reactions caused by histamine. The H1 blockers have been used to control pruritus and skin inflammation, rhinorrhea, and airway inflammation. Cetirizine is considered a second-generation antihistamine to distinguish it from other, older antihistamines. The most important difference between cetirizine and older drugs is that it do
Cetirizine is used to treat and prevent allergic reactions in people. It is preferred over older drugs because it has fewer side effects. In dogs and cats it has been considered for pruritus therapy, allergic airway disease, rhinitis, and other allergic conditions. In cats, 1 mg/kg (5 mg/cat) has produced plasma concentrations considered effective. However, it was not effective in decreasing the inflammatory response in cats with hyper-responsive airways (experimentally induced asthma). In dogs, doses of 2 mg/kg suppress histamine response for 8 hours. However, there are no published clinical
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
獸醫須先確認精確鹽型、單方或複方、完整成分與強度基準、實際濃度、物種、體重、診斷、急慢性與嚴重度、既往反應、併用藥、肝腎狀態、生殖狀態及預定檢查,再裁決是否使用。犬慢性異位性皮膚炎試驗、貓開放試驗、健康動物藥動與挑戰資料不得合併成自動劑量或療效承諾。
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。
renal