A precursor to pantothenic acid, dexpanthenol acts as a precursor to coenzyme A that is necessary for acetylation reactions to occur during gluconeogenesis and in the production of acetylcholine. It has been postulated that post-surgical ileus can be prevented by giving high doses of dexpanthenol, thereby assuring adequate levels of acetylcholine. However, one study in normal horses (Adams, Lamar, and Masty 1984) failed to demonstrate any effect of dexpanthenol on peristalsis.
Dexrazoxane may be useful to attenuate the cardiotoxic effects of doxorubicin in patients who are showing signs of anthracycline cardiotoxicity, have cardiac disease, or are at maximum cumulative dosages of doxorubicin. It is also used to treat extravasation injuries associated with doxorubicin. While dexrazoxane has been shown to be cardioprotective when given at dosages of 10 times the doxorubicin dose, there is evidence that it may also partially protect the cancer cells being treated.
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
公開資料只能確認分子身分、一份舊版商業獸醫標籤轉錄、產品 SDS、有限且不支持明確療效的研究,以及人用標籤邊界;無法建立可執行的犬、貓或馬胃腸療程。所有數值只作證據邊界卡,不得直接進入計算器、處方或飼主衛教。
DRUGAPI 劑量審查引用的獸醫官方標示(各標示只適用於其產品、物種與法域,不可互換)
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。