商品名：Prostigmin, Stiglyn, Neostigmine bromide, and
Cholinesterase inhibitor. Anticholinesterase drug and antimyasthenic drug. This drug inhibits the enzyme that metabolizes acetylcholine into inactive products. Therefore it prolongs the action of acetylcholine at the synapse. The major difference between physostigmine and neostigmine or pyridostigmine is that physostigmine crosses the blood–brain barrier, and the others do not.
Neostigmine is used as an antidote for anticholinergic intoxication. It is also used as a treatment for myasthenia gravis, treatment (antidote) for neuromuscular blockade, and treatment for ileus. It also has been used as a treatment of urinary retention— such as the retention observed in postoperative patients—by increasing the tone of bladder smooth muscle. In ruminants, it has been used to stimulate rumen and intestinal motility.
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
現行資料含 100 倍馬匹小數錯誤，並混合大動物標示品、重症肌無力與麻醉研究；體重-only 輸出不安全。
DRUGAPI 劑量審查引用的獸醫官方標示（各標示只適用於其產品、物種與法域，不可互換）
renal