商品名:Antilirium
Cholinesterase inhibitor. Anticholinesterase drug. This drug inhibits the enzyme that breaks down acetylcholine. Therefore it prolongs the action of acetylcholine at the synapse. The major difference between physostigmine and neostigmine or pyridostigmine is that physostigmine crosses the blood–brain barrier, and the others do not.
Physostigmine is used as an antidote for anticholinergic intoxication and as a treatment (antidote) for neuromuscular blockade. It has also been used as a 612 Phytonadione treatment of ileus and urinary retention (such as postoperative urine retention) by increasing the tone of the bladder smooth muscle.
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
現有數字混合急救、單例、研究與食品動物情境,且產品濃度/賦形劑差異大;未具備 ICU toxicology、ECG、airway/ventilation、atropine 與法律 gate 時全部 fail closed。
DRUGAPI 劑量審查引用的獸醫官方標示(各標示只適用於其產品、物種與法域,不可互換)
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。