商品名:Lutalyse, Prostin F2 alpha, ProstaMate, Prostaglandin
Dinoprost is a prostaglandin (PGF2 alpha) that induces luteolysis. Prostaglandin F2 and its analogs have a direct luteolytic action on the corpus leuteum. After injection, it will produce a functional regression of the corpus luteum (Luteolysis). In nonpregnant cycling cattle, this effect will result in starting estrus 2 to 5 days after injection. In pregnant animals, it will terminate pregnancy. In animals with prolonged luteal activity that have pyometra, mummified fetus, or luteal cysts, the luteolysis usually results in resolution of the problem and return to normal cycling.
Dinoprost is used for estrus synchronization in cattle and horses by causing luteolysis. In horses and cattle it is used to control timing of estrus in estrus-cycling females and in clinically anestrus females that have a corpus luteum. In pigs, dinoprost is used to induce parturition when given within 3 days of farrowing. In dogs, dinoprost has been used to treat open pyometra. In cattle, dinoprost has been used for treatment of chronic endometritis. In large animals, dinoprost is used to induce abortion in the first 100 days of gestation, but use for inducing abortion in small animals has been questioned.
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
確認藥物確為 Dinoprost Tromethamine,並分開鹽量與 dinoprost 有效部分基準 確認精確產品、濃度、賦形劑、批次、標示、法域與許可狀態 確認物種、體重、生殖目的、黃體狀態、妊娠階段、診斷與全身穩定度 確認核准或仿單外身分、食用動物殘留規則及所有併用藥物 由獸醫師定義監測、有效反應、停止條件、不良反應處置與緊急手術或其他救援 拒絕舊資料、別名、同類藥或來電者提供數值所產生的自動計算與處方
DRUGAPI 劑量審查引用的獸醫官方標示(各標示只適用於其產品、物種與法域,不可互換)
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。