商品名：Doribax
Beta-lactam antibiotic of the carbapenems class with broad spectrum of activity. Action on cell wall is similar to other beta-lactams, which is to bind penicillin- binding proteins (PBP) that weaken or interfere with cell wall formation. In Escherichia coli and Pseudomonas aeruginosa, doripenem binds to PBP 2, which is 260 Doripenem involved in the maintenance of cell shape, and to PBPs 3 and 4. Carbapenems have a broad spectrum of activity and are among the most active of all antibiotics. Doripenem has similar activity as imipenem and meropenem to include gram- negative bacilli, including Enterobacteriaceae and Pseudomonas aeruginosa. It is slightly more active against Pseudomonas aeruginosa. It also is active against most gram-positive bacteria, except methicillin-resistant strains of St
Doripenem is indicated primarily for resistant infections caused by bacteria resistant to other drugs. It is especially valuable for treating resistant infections caused by Pseudomonas aeruginosa, Escherichia coli, and Klebsiella pneumoniae. Doripenem is not used in veterinary medicine as commonly as meropenem or imipenem.
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
D0244 只保留多尼培南（Doripenem）精確身分與不可執行的參考證據。精確產品、犬或貓的臨床感染診斷、物種適用的感受性判讀、治療暴露、臨床療效、重複治療安全性、監測及法規治理尚未共同確認，因此不得啟用物種、給藥途徑、適應症、劑量、交互作用配對、處方或副作用發生頻率。
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。