商品名：Invanz
Ertapenem is a beta-lactam antibiotic of the carbapenem (penem) class with a broad spectrum of activity. Its action on cell walls is similar to other beta-lactams, which is to bind penicillin-binding proteins (PBP) that weaken or interfere with cell wall formation. In Escherichia coli, it has strong affinity toward PBPs 1a, 1b, 2, 3, 4, and 5 with preference for PBPs 2 and 3. Ertapenem is stable against hydrolysis by a variety of beta-lactamases, including penicillinases, and cephalosporinases and extended spectrum beta-lactamases. Spectrum includes gram-negative bacilli, including Enterobacteriaceae. Ertapenem is not as active against Pseudomonas aeruginosa as other carbapenems. It is also active against most gram-positive bacteria, except methicillin-resistant strains of Staphylococcus a
Erythromycin is used in a variety of species to treat infections caused by susceptible bacteria. Infections treated include respiratory infections (pneumonia), soft tissues infections caused by gram-positive bacteria, and skin and respiratory infections. In foals it is used to treat Rhodococcus equi pneumonia, often in combination with Erythromycin 289 E rifampin. In some species, including horses, it has been used at low doses to stimulate intestinal motility but demonstration of this activity has been limited in clinical patients. In horses the dose of erythromycin to stimulate GI motility is lower than the antibacterial dose (1 mg/kg), but the clinical efficacy for this use has not been shown. In experimental calves, 8.8 mg/kg IM significantly increased rumen motility. At a dose of 10 m
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
確認培養與藥敏結果及病原體對替代抗菌藥的反應 確認使用法域、獸醫法規及抗菌藥管理要求 確認物種、體重、腎功能、神經病史及過敏史 確認精確商品、有效成分與鹽類、濃度、稀釋液、相容性及保存條件 完成個案化藥動藥效目標、監測及降階計畫
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。
90%
4 hours
renal