商品名:Oxyglobin
Hemoglobin glutamer (bovine) is used as oxygen-carrying fluid in dogs with varying causes of anemia. Oxyglobin is an ultrapurified polymerized bovine hemoglobin. The molecular weight is 64,000-500,000 (average 200,000). Osmolality is 300 mOsm/ mL. Colloid osmotic pressure is higher than other colloids, with a colloid osmotic pressure of 43.3. Half-life in dogs is approximately 24 hours (range 18-43 hours). It is metabolized by macrophages, and 95% of a dose is eliminated in 5-9 days.
Hemoglobin glutamer has been used to treat anemia caused by blood loss, hemolysis, or decreased blood cell production. Although approved for dogs, it also has been used in cats.
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
確認手上精確產品、包裝完整性、有效期限、產品標籤、法域核准與實際供應來源。 確認物種與適應症;犬標籤不得自動外推到貓、馬或小馬駒。 評估貧血病因、嚴重度、循環容量、心臟功能、腎臟尿量、活動性出血與同時使用的液體或血品。 由可辨識並處理循環負荷與急性呼吸惡化的獸醫團隊制定個別計畫並持續監測。 在解讀血清化學、凝血、尿液、乳酸與血紅蛋白結果前確認分析儀與方法是否受細胞外血紅蛋白干擾。
DRUGAPI 劑量審查引用的獸醫官方標示(各標示只適用於其產品、物種與法域,不可互換)
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。