商品名:Intralipid (Fresenius Kabi)
IV lipid emulsion (ILE) acts as a 'lipid sink' that sequesters lipophilic toxins from target tissues (especially the heart and CNS), reducing their tissue concentrations. Also provides a metabolic fuel source for the myocardium, enhancing cardiac function during toxicosis. Key antidote for local anesthetic systemic toxicity (LAST) and other lipophilic drug overdoses.
Lipophilic drug/toxin overdose: local anesthetic toxicity (bupivacaine, lidocaine), ivermectin toxicity, permethrin toxicosis (cats), calcium channel blocker OD, baclofen OD.
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
限急診或加護團隊在即時監測與完整復甦能力下,依確認或高度懷疑毒物、臨床嚴重度與毒理諮詢個案化評估。先完成病患穩定、去污染、呼吸與通氣、抽搐、循環及毒物專一治療;再核對具名產品、濃度、容器、完整配方、無菌狀態、導管與相容性。治療前盡可能留取檢體;治療中與治療後追蹤神經、呼吸與氧合、心血管、灌流、體溫、導管、脂血、三酸甘油脂、酸鹼、電解質、血糖、肝腎、排尿量與尿檢、血球及凝血,並聯絡實驗室確認脂血干擾。
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。