商品名:Program
Antiparasitic. Lufenuron is a benzoylurea insecticide. This class of insecticides was previously used on fruits to decrease damage by insects. Lufenuron (Program) has been used for prevention of flea infections in dogs and cats because it inhibits chitin synthesis. For this use it has been given to dogs at a dose of 10 mg/kg every 30 days and to cats at a dose of 30 mg/kg every 30 days. It may also have some inhibition on fungal cell membranes because it inhibits the cell wall of fungi, which contain chitin, and other complex polysaccharides. Because of this property on fungal cell membranes there has been interest in using lufenuron to treat dermatophytes in small animals. However, proven efficacy has been controversial.
Lufenuron is used to control flea infestations by preventing hatching of eggs. It has been used as part of flea control, often with other drugs that kill adult fleas. Lufenuron has been combined with milbemycin in formulations for small animals, and additional details may be found in the section on milbemycin. There are clinical reports of the use of lufenuron for treating dermatophyte infections in small animals—particularly cats—at high doses of 80-100 mg/kg orally. However, endorsement of this use has diminished and dermatologists have disputed the efficacy and have observed a high incidence of recurrence. In horses lufenuron was not absorbed orally and is not effective for treating fungal infections. It does not have any in vitro effect on Aspergillus fumigatus or Coccidioides immitis.
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
確認 lufenuron 母體分子、精確品牌與成品、單方或複方、劑型、規格、濃度、賦形劑、製造商、批次、來源、完整性、法域與目前核准及供應狀態。 確認物種、品種、年齡、體重、生理與繁殖狀態、是否為食用動物、診斷、蚤害生命週期目標、共病、皮膚狀態及先前處置。 依精確成品核對數值基礎、途徑、時程、療程、重複處置、監測、成蚤控制、停止與轉診計畫;不得由本資料自動產生。 逐一核對所有藥物、補充品、外用與環境除蚤品、農藥或可能誤食,複方及共同使用不得視為已評估交互作用。 皮癬菌感染不得依舊病例或舊資料使用 lufenuron;應依現行獸醫皮膚科診斷與治療共識選擇方案。 逐一人工裁決藥對;受保護 peer 不得由對側 none、evaluated 或 override 解除。
DRUGAPI 劑量審查引用的獸醫官方標示(各標示只適用於其產品、物種與法域,不可互換)
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。
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