商品名:Telmintic, Telmin, Vermox (human preparation), and
Benzimidazole antiparasitic drug. Like other benzimidazoles, mebendazole produces a degeneration of the parasite microtubule and irreversibly blocks glucose uptake in parasites. Inhibition of glucose uptake causes depletion of energy stores in the parasite, eventually resulting in death. However, there is no effect on glucose metabolism in mammals.
Mebendazole is used in horses for treatment of infections caused by large roundworms (Parascaris equorum), large strongyles (Strongylus edentatus, S. equinus, and S. vulgaris), small strongyles, and mature and immature (fourth larval stage pinworms [Oxyuris equi]). In dogs it has been used for treatment of infections of roundworms (Toxocara canis), hookworms (Ancylostoma caninum and Uncinaria stenocephala), whipworms (Trichuris vulpis), and tapeworms (Taenia pisiformis).
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
先核對實際產品、完整成分與現行標籤。 確認物種、體重、寄生蟲與生活史、診斷依據及當地抗藥性。 確認食用動物身分、產乳用途、司法管轄區與停藥規定。 若為複方,分別檢查其他活性成分的禁忌、交互作用、過量與環境風險。 不要由歷史文件、人體產品或小型研究自動產生處方。
DRUGAPI 劑量審查引用的獸醫官方標示(各標示只適用於其產品、物種與法域,不可互換)
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。