商品名:Merrem
Beta-lactam antibiotic of the carbapenem class (also known as penems) with broad spectrum of activity related to imipenem. Action on the cell wall is similar to other beta-lactams, which is to bind penicillin-binding proteins (PBP) that weaken or interfere with cell wall formation. The carbapenems bind to a specific PBP (PBP-1) that results in more rapid lysis compared to other beta-lactams. This results in greater bactericidal activity and a longer postantibiotic effect. Carbapenems have a broad spectrum of activity and are among the most active of all antibiotics. Spectrum includes gram-nega
Meropenem is indicated primarily for resistant infections caused by bacteria resistant to other drugs. It is especially valuable for treating resistant infections caused by Pseudomonas aeruginosa, Escherichia coli, and Klebsiella pneumoniae. Meropenem is slightly more active against some bacteria than imipenem.
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
確認精確 meropenem 活性成分、水合型、商品或調劑來源、劑型、強度、賦形劑、批次、保存、相容性、法域與可得性 確認物種、體重、感染部位、嚴重度、培養、感受性方法、適用 breakpoint、MIC、採樣時間、感染源控制與可用替代抗菌藥 評估腎功能、神經病史、過敏史、繁殖狀態、透析方式、液體狀態與全部合併藥,特別核對 probenecid、valproic acid 或其他可能改變暴露與風險的藥物 由負責醫師事先定義療效、培養追蹤、器官功能、神經與過敏監測,以及暫停、調整、重啟、救援、轉診與抗菌藥降階條件 不得從人用標示、健康動物藥動、單一病例、模擬 breakpoint 或舊 runtime 拼接處方
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。
84%
renal