商品名:New Methylene Blue and generic brands
Methylene blue acts as a reducing agent to reduce methemoglobin to hemoglobin. The action of methylene blue is particularly important when it is used to convert methemoglobin to hemoglobin in erythrocytes. It is reduced to leucomethylene blue in the body by combining with reduced nicotinamide adenine dinucleotide phosphate (NADPH) in the presence of NADPH reductase. Leucomethylene blue then transfers an electron to reduce methemoglobin to hemoblobin. Methemoglobin occurs as the result of oxidative damage to hemoglobin, and methylene blue has been used as an antidote for intoxication. Sources of intoxication in animals that cause methemoglobinemia include exposure to nitrate, nitrite, or chlorate in ruminants; acetaminophen and naphthalene (mothballs) in cats (and occasionally dogs); and lo
Methylene blue is used to treat methemoglobinemia caused by chlorate and nitrate toxicosis. It also has been used to treat cyanide toxicosis.
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
須先核對 CID 6099 亞甲藍而非 CID 73518 新亞甲藍,再確認精確成品、濃度、賦形劑、動物種類、診斷或毒物、嚴重度、途徑、劑量基準、間隔、重複上限、順序或持續時間、G6PD 與紅血球還原能力、血清素性併用、腎肝功能、監測、停止與救援規則、食用動物身分、殘留建議及法域現況。
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。
renal