商品名：Capstar
Nitenpyram is an antiparasitic drug used for treatment of fleas. It will rapidly kill adult fleas. It is from the class of synthetic insecticides known as the neonicotinoids. It is related to imidacloprid and has the same mechanism of action, which is to inhibit postsynaptic nicotinic acethycholine receptors, which produces influx of sodium ions. Nitenpyram is absorbed completely (100%) from oral administration and has a half-life in dogs and cats of 2.8 and 7.7 hours, respectively. After oral absorption it produces a rapid kill of adult fleas that has been observed as quickly as 30 minutes after drug administration, and is 98.6% effective in dogs, and 98.4% effective in cats.
Nitenpyram is used to kill fleas on dogs and cats. It produces a rapid kill with fleas killed within an hour of administration. It is often used with other drugs that act to prevent flea infestations as part of a comprehensive flea-control program.
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
核准方案採固定錠數體重帶，不是 1 mg/kg 線性換算。須核對產品、物種、年齡、體重與適應症；NWS 的 6 小時間隔兩劑是臨時 EUA，須與除蚤再次給藥分開。
DRUGAPI 劑量審查引用的獸醫官方標示（各標示只適用於其產品、物種與法域，不可互換）
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