商品名:Pentaspan
Pentastarch is a synthetic colloid volume expander that is used to maintain vascular volume in animals with circulatory shock. It is prepared from hydroxyethyl starch and is derived from amylopectin. There are two hydroxyethyl starch preparations: hetastarch and pentastarch. Hetastarch (6%) has an average molecular weight of 450,000 and colloid osmotic pressure of 32.7. Pentastarch (10%) has an average molecular weight of 280,000 and colloid osmotic pressure of 40. Because hetastarch is a larger molecular weight compound than pentastarch, it tends to remain in the vasculature and prevent loss of intravascular volume and tissue edema. After administration, pentastarch will be retained in the vasculature and prevent loss of intravascular volume and tissue edema. Other colloids used are dextr
Pentastarch is used primarily to treat acute hypovolemia and shock. It is administered IV in acute situations. Pentastarch has a duration of effective volume expansion of 12-48 hours. Pentastarch is used in similar situations as hetastarch, but it is used less frequently.
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
精確 Pentastarch 犬貓劑量未獲驗證,歷史 PENTASPAN 已註銷,且不同 HES 產品不可互換。過敏、出血/凝血異常、液體負荷與腎損傷風險要求院內監測及替代方案審查。
DRUGAPI 劑量審查引用的獸醫官方標示(各標示只適用於其產品、物種與法域,不可互換)