商品名：HES, Hydroxyethyl starch, Hetastarch, and
Hetastarch is a synthetic colloid volume expander that is used to maintain vascular volume in animals with circulatory shock. It is a modified branched-chain glucose polymer prepared from hydroxyethyl starch and is derived from amylopectin. There are two hydroxyethyl starch preparations: hetastarch and pentastarch. Hetastarch (6%) has an average molecular weight of 450,000 and colloid osmotic pressure of 32.7. Pentastarch (10%) has an average molecular weight of 280,000 and colloid osmotic pressure of 40. Because hetastarch is a larger molecular weight compound than pentastarch, it tends to remain in the vasculature and prevent loss of intravascular volume and prevent tissue edema. Other colloids used are dextrans (Dextran 40 and Dextran 70).
Hetastarch is used primarily to treat acute hypovolemia and shock. It is administered IV in acute situations. Hetastarch has a duration of effective volume expansion of 12-48 hours. One of the disadvantages to use of hetastarch is the high cost. Hetastarch 363 H Instructions for Use Suspend in saline (0.9%) or 5% dextrose solution for use. Administer in 5-mL/kg increments to small animals, then reassess and increase the dose to rates listed in the dosing section. Hetastarch is used in critical care situations, and it is infused via constant rate infusion (CRI). Hetastarch appears to be more effective and produce fewer side effects than Dextran. Infuse slowly. Patient Monitoring and Laboratory Tests Monitor patient’s hydration status and blood pressure during administration. Monitor heart r
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
由院內獸醫確認確切聚合物分子量、取代度、濃度、載體、商品、批次來源、司法管轄與目前可得性。 先評估低血容量與灌流狀態、替代治療、腎功能與尿量、凝血與出血、血小板、血比容、肺部與容量負荷、肝臟、電解質及酸鹼狀態。 犬、貓、成人馬與仔馬證據必須分開；tetrastarch、pentastarch、HEXTEND 與 saline 成品不得自動互換。 所有公開研究方案與人用標籤數值只能作不可執行證據，不得進入計算、處方或飼主內容。
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。
renal