商品名:Pilocarpine hydrochloride*
Direct-acting parasympathomimetic that stimulates cholinergic receptors. It lowers intraocular pressure by causing ciliary body muscle contraction, miosis and improved aqueous humour outflow.
Has been used in the management of glaucoma, although this role has been superseded by other topical drugs such as carbonic anhydrase inhibitors and prostaglandin analogues. Pilocarpine produces miosis in 10–15 min for 6–8 hours in the dog. Oral pilocarpine increases lacrimation and can be used in the management of neurogenic keratoconjunctivitis (KCS or dry eye) in the dog; topical ophthalmic pilocarpine can also be used but can be irritant. Pilocarpine is rarely used for ophthalmic purposes in
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
現有犬貓 mg/kg 劑量是錯誤 Cardiac 分類的自動產物。犬神經性乾眼的公開濃度+滴數方案彼此不一致,貓證據僅病例或正常眼單次研究;正式方案需綁定濃度、滴管、途徑、適應症、調整與停藥規則。
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。