In erythrocytes, pyridoxine is converted to pyridoxal phosphate and, to a lesser extent, pyridoxamine, which serve as coenzymes for metabolic functions affecting protein, lipid and carbohydrate utilization. Pyridoxine is necessary for tryptophan conversion to serotonin or niacin, glycogen breakdown, heme synthesis, synthesis of GABA in the CNS, and oxalate conversion to glycine. Pyridoxine can act as an antidote by enhancing the excretion of cycloserine or isoniazid. Pyridoxine requirements increase as protein ingestion increases.
Antihistamines are used in veterinary medicine to reduce or help prevent histamine mediated adverse effects; predominantly used in horses.
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
犬資料分屬異煙肼急救、單一歷史 crimidine 病例、Doxil 研究及高劑量毒理；貓缺乏可核對療程，且未確認現行獸醫單方產品與台灣法域。所有數值、物種與飼主劑量維持封鎖。
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。