商品名:Omnizole, Equizole, TBZ, and Thibenzole
Benzimidazole antiparasitic drug. Like other benzimidazoles, it produces a degeneration of the parasite microtubule and irreversibly blocks glucose uptake in parasites. Inhibition of glucose uptake causes depletion of energy stores in parasite, eventually resulting in death. However, there is no effect on glucose metabolism in mammals.
Availability of commercial forms of thiabendazole has been limited. In horses, thiabendazole has been used for control of large and small strongyles; Strongyloides; and pinworms of the genera Strongylus, Cyathostomum, Cylicobrachytus and related genera Craterostomum, Oesophagodontus, Poteriostomum, and Oxyuris. In ruminants it has been used for infections of GI roundworms in sheep and goats (Trichostrongylus spp. Haemonchus spp., Ostertagia spp., Cooperia spp., Nematodirus spp., Bunostomom spp., Strongyloides spp., Chabertia spp., Oesophagostomum spp., Trichostrongylus colubriformis and T. axei, and Ostertagia spp.).
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
任何臨床使用前,應以 D0636 canonical 記錄為身分入口,且不得從 D0641 退役別名繼承 payload;再由獸醫師核對確切商品與 application、所有有效成分與強度、單方或複方、物種、途徑、適應症與病原、法域、核准與實際供應日期、食品鏈身分、共同用藥、局部或全身暴露、肝腎與過敏風險,以及確切商品標示。現有公開證據不足以開啟通用計算、處方、交互作用或副作用頻率層級。
DRUGAPI 劑量審查引用的獸醫官方標示(各標示只適用於其產品、物種與法域,不可互換)
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。
renal