Tiamulin is usually a bacteriostatic antibiotic, but can be bactericidal in very high concentrations against susceptible organisms. The drug acts by binding to the 50S ribosomal subunit, thereby inhibiting bacterial protein synthesis. Tiamulin has good activity against many gram-positive cocci, including most Staphylococci and Streptococci (not group D streps). It also has good activity against Mycoplasma and spirochetes. With the exception of _Haemophilus_ spp. and some _E. coli_ and Klebsiella strains, the drug’s activity is quite poor against gram-negative organisms.
A ticarcillin disodium product was approved for intrauterine use in horses in the treatment of endometritis in horses caused by beta hemolytic streptococci, but is apparently no longer marketed. Ticarcillin disodium injection is used in veterinary species in the treatment of systemic _Pseudomonas aeruginosa_ infections, often in combination with an appropriate aminoglycoside agent. When compared with carbenicillin, ticarcillin is about twice as potent (on a per weight basis) in the treatment against susceptible Pseudomonas. Synergy may occur against some Pseudomonas strains when used in combination with aminoglycosides, but _in vitro_ inactivation of the aminoglycoside may also occur (see Drug Interactions) if the 878 ticarcillin disodium drugs are physically mixed together or in patients with severe renal failure. Ticarcillin (alone and with clavulanate) has been used in a variety of compounded preparations for otic use.
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
24 張現行標籤／法規數值卡全部 non-executable。live 兩項豬用飲水換算值雖可追溯到一項美國產品，卻缺少精確產品、tiamulin hydrogen fumarate 基準、濃度、法域、實際飲水量、離子載體飼料稽核與停藥期；犬貓支援則無本輪現行產品證據。離子載體名單與前後間隔亦隨產品不同，不能建立通用安全名單。未關閉所有閘門前，禁止計算、處方、飼主數值與食用動物執行。
DRUGAPI 劑量審查引用的獸醫官方標示（各標示只適用於其產品、物種與法域，不可互換）
renal