商品名：Micotil and Pulmotil tilmicosin premix
Macrolide antibiotic. It inhibits bacteria by binding to 50S ribosome and inhibiting protein synthesis. The spectrum of activity is limited primarily to gram-positive aerobic bacteria; Mycoplasma; and respiratory pathogens such as Pasteurella multocida, Mannheimia haemolytica, and Histophilus somni (formerly Haemophilus somnus). Tilmicosin administered to calves (15 mg/kg SQ) reduced expression of prostaglandin (PGE2) stimulated by bacteria. There also may be some anti- inflammatory effects such as reduced leukocyte release of inflammatory mediators in the lungs associated with tilmicosin treatment. There also may be reduced prostaglandin synthesis with tilmicosin administration in alveolar macrophages.
Tilmicosin activity against respiratory pathogens is effective for treating bovine respiratory disease (BRD). In cattle, one injection has duration of at least 72 hours, based on high concentrations achieved in lung. Tilmicosin also has been used as a prophylactic treatment for calves that are entering feedlots. The use of tilmicosin at the time of feedlot arrival has reduced incidence of respiratory disease in cattle. Tilmicosin (Pulmotil) is used in medicated feed for swine for control of swine respiratory disease (SRD).
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
現行服務無法端到端強制精確商品、有效部分與鹽基準、法域、物種與生產類別、呼吸道診斷與病原、注射安全裝置、混料或飲水準備、攝食飲水假設、監測、重新評估、停藥期、食物鏈及人員急救合約。兔在現行美國 Micotil 是非目標暴露死亡通報，但只在分離的歐盟兔用預混料 referral 合約中才是目標物種；兩者均不得變成通用支持。故物種、途徑、適應症、劑量、交互作用與五層通用不良反應全部留空。
DRUGAPI 劑量審查引用的獸醫官方標示（各標示只適用於其產品、物種與法域，不可互換）
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。