Tiludronate, like other bisphosphonates, inhibit osteoclastic bone resorption by inhibiting osteoclast function after binding to bone hydroxyapatite thereby helping to regulate bone remodeling.
Little information is presently available on the use of tinidazole in dogs, cats, or horses. It potentially could be useful for treating anaerobic infections, particularly associated with dental infections in small animals. Because of its antiprotozoal effects, it has been used as an alternative for treating giardiasis in small animals, and it could have efficacy against amebiasis, trichomoniasis or balantidiasis in veterinary species, but documentation of efficacy is not available. Tinidazole has a longer duration of action in dogs and cats than does metronidazole. In humans, oral tinidazole is FDA-approved for treating extraintestinal and intestinal amebiasis, ( _Entamoeba histolytica_ ), giardiasis ( _Giardia duodenalis/lamblia_ ), and trichomoniasis ( _T. vaginalis_ ).
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
46 張數值證據卡全部 non-executable。live 的 0.1 mg/kg q24h 脫離舊十日療程脈絡,且犬貓每四週 IV、tinidazole 用途、舊 50 mg 配製、通用鹽/酸換算及全球停藥期均屬污染或錯配。通用 API 無法同時強制精確產品、活性基質、馬、適應症、輸注流程、水合/腎功能、NSAID、電解質、HYPP、年齡、繁殖、食品/比賽身分與法域,因此禁止計算、處方與飼主數值。
DRUGAPI 劑量審查引用的獸醫官方標示(各標示只適用於其產品、物種與法域,不可互換)
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。
4.5 hours
renal