商品名:Desyrel and generic
Trazodone is an antianxiety agent. It is a triazolopyridine derivative amd belongs to the phenylperazine group of centrally acting drugs. It acts both as a serotonin 2A (5-HT2A) receptor antagonist and a serotonin reuptake inhibitor (SSRI), with little effect on dopamine. It also has nonspecific sedating properties and is used as a sedative and hypnotic. It has an active metabolite that also may have effects on the serotonin-1 receptor. The action as an antidepressant and antianxiety agent appears to be distinct from tricyclic antidepressants and SSRIs. It is highly metabolized in people, but
Trazodone has been used in dogs for events that trigger anxiety such as visits to the veterinarian, thunderstorms, noise phobias, travel in a car, and other phobias and generalized anxiety events. Although trazodone has been helpful to relieve anxiety in these situations, it has a delayed onset of activity, and can be unpredictable. To optimize the effects, it should be administered approximately 1 hour prior to an anticipated anxiety-inducing event. Trazodone Hydrochloride 773 T Instructions for Use Start with a low dose (approximately 2 mg/kg) and work up gradually to higher doses, as needed
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
由獸醫師確認動物種類、完整病史與本次臨床目的 由獸醫師核對實際產品、濃度、併用藥與心血管、肝臟、出血及神經風險 由獸醫師個別開立並提供監測與緊急處置指示 未完成上述確認時不得啟用計算、處方、飼主數字指示或自動交互作用
DRUGAPI 劑量審查引用的獸醫官方標示(各標示只適用於其產品、物種與法域,不可互換)