商品名:Draxxin and Macrolide
Antibacterial related to the macrolide class of drugs. It is considered a triamilide macrolide, which is derived from azalide macrolides, such as azithromycin. Like other macrolides it inhibits bacterial protein synthesis by binding to the ribosomal 50S subunit. It is considered bacteriostatic, but it may have bactericidal properties in vitro. Because of a positively charged molecule, it may penetrate gram-negative bacteria more easily than other macrolide antibiotics. Tulathromycin has a spectrum of activity that is limited to gram-positive bacteria and some gram-negative bacteria that cause respiratory diseases in cattle and pigs (e.g., Mannheimia haemolytica, Mycoplasma, and Pasteurella multocida). The half-life is long (e.g., 92-hour plasma half-life and 8-day tissue half-life in cattl
In cattle, tulathromycin is used for treatment of bovine respiratory disease (BRD) caused by Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni (formerly Haemophilus somnus). It is also effective for treating infections caused by Mycoplasma. It also has been used to prevent infections caused by these pathogens when used prophylactically. A single dose has been effective for bovine infectious keratoconjunctivitis (Moraxella bovis). In pigs, it has been used for treatment of swine respiratory disease (SRD) associated with Actinobacillus pleuropneumoniae, P. multocida, Bordetella bronchiseptica, and H. parasuis. In foals, tulathromycin has been used for treatment of pulmonary abscesses.
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
確認精確單方產品、濃度、劑型、容器與現行版本,不得以 Draxxin KP/Plus 或任何泰拉黴素加酮洛芬複方替代。 確認法域、核准及實際供應狀態、物種、生產類別、年齡或體重、疾病、病原體,以及治療或控制語意。 確認途徑、部位、每部位上限、精確劑量契約、食用動物屠宰與乳品限制。 依現行標示評估過敏、妊娠泌乳、抗菌藥審慎使用、反應與升級處置。 任何交互作用配對需雙方精確身分、獸醫物種與情境、後果、嚴重度及臨床處置完整證據。
DRUGAPI 劑量審查引用的獸醫官方標示(各標示只適用於其產品、物種與法域,不可互換)
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。
88%
2.75 days