商品名:Vancocin and Vancoled
Antibacterial drug. Vancomycin is bactericidal for most organisms and bacteriostatic for enterococci. It inhibits the cell wall by binding to the D-alanyl-D-allanine portion of cell wall precursors and interfering with the bacterial cell wall. The bactericidal action occurs by activating bacterial cell wall autolysins. Spectrum includes Streptococcus, Enterococcus, and Staphylococcus. Strains of Staphylococcus treated often are called methicillin-resistant Staphylococcus (e.g., methicillin-resistant Staphylococcus aureus [MRSA] or Staphylococcus pseudintermedius [MRSP]).
Vancomycin is used for resistant strains of Staphylococcus or Enterococcus in animals. It is the most common injectable drug to treat methicillin-resistant Staphylococcus species and drug-resistant Enterococcus spp. It is not effective against gram-negative bacteria. Vancomycin use is not common in animals because it is inconvenient to administer. However, it can be valuable for treatment of enterococci or staphylococci that are resistant to other antibiotics. It also has been administered orally to people for diarrhea caused by Clostridium spp. Occasionally it has been used in horses for loca
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
必須逐案確認物種、食用動物身分、培養與藥敏、感染部位、替代藥物、腎臟狀態、合併腎毒性暴露、精確製品與監測計畫,並由獸醫感染症與臨床藥理專業人員共同審核。
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。