商品名:Apokyn and generic brands
Emetic drug. Apomorphine is a potent lipophilic agent that crosses the blood–brain barrier and stimulates dopamine (D2) receptors in the vomiting center. It promptly causes vomiting in dogs. Although it is easily absorbed from mucosal surfaces (e.g., conjunctiva of the eye), it is not absorbed orally because of first-pass effects.
Apomorphine is indicated for inducing emesis in animals that have ingested toxic agents. After subcutaneous administration, the onset of effect is 10 minutes or shorter. It is promptly effective for inducing vomiting in dogs but less so in cats. Apomorphine also is absorbed from mucosal administration after applying to the conjuctiva of the eye. Xylazine often is a more reliable emetic in cats.
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
啟用前必須同時鎖定 apomorphine 活性、hydrochloride 與 hydrate、free-base 或鹽基準、商品、濃度、劑型、途徑、犬隻身分、催吐適切性、攝入物與時間、吞嚥及咽反射、神經呼吸循環狀態、吸入風險、生殖與肝臟狀態、監測及救援能力、法域、食物鏈及雙向交互作用紀錄。
DRUGAPI 劑量審查引用的獸醫官方標示(各標示只適用於其產品、物種與法域,不可互換)
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。