Exogenously supplied ascorbic acid is a dietary requirement in some exotic species (including rainbow trout, Coho salmon), guinea pigs, and in primates. The other domestic species are able to synthesize _in_ _vivo_ enough Vitamin C to meet their nutritional needs. Vitamin C is used for tissue repair and collagen formation. It may be involved with some oxidation-reduction reactions, and with the metabolism of many substances (iron, folic acid, norepinephrine, histamine, phenylalanine, tyrosine, some drug enzyme systems). Vitamin C is believed to play a role in protein, lipid and carnitine synthesis, maintaining blood vessel integrity and immune function.
Asparaginase has been useful in combination with other agents in the treatment of lymphoid malignancies. The drug is most useful in inducing remission of disease but is occasionally used in maintenance or rescue protocols. Use of asparaginase as part of an initial treatment lymphosarcoma protocol is now somewhat controversial, as one study (MacDonald, Thamm et al. 2005) in dogs showed no statistical difference for response rates, remission or survival rate, remission or survival duration, or prevalence of toxicity and treatment delay in dogs treated with or without asparaginase as part of a standard CHOP protocol.
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
DRUGAPI 劑量審查引用的獸醫官方標示（各標示只適用於其產品、物種與法域，不可互換）
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。
renal