商品名：Colcrys and generic brands
Anti-inflammatory agent. It inhibits fibrosis and formation of collagen.
In people, colchicine is used to treat gout. In animals it has been used as an antifibrotic agent to decrease fibrosis and development of hepatic failure (possibly by inhibiting formation of collagen). Anti-inflammatory effects may be caused from inhibition of neutrophil and mononuclear migration. Antifibrotic effects result from blockage of microtubular-mediated transcellular movement of proteins and to inhibit secretion of procollagen molecules into the extracellular matrix. It has also been used in animals to control amyloidosis. In Shar Pei dogs, colchicine has been used to treat a fever s
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
確認精確有效成分、產品、劑型、強度、來源與調劑品質，不得把錠劑、液劑、微球、複方或植物暴露互換 確認動物種類、Shar-Pei 血統、臨床診斷、是否僅為基因風險、是否已有腎或肝澱粉樣變性，以及治療目標是發作控制、預防或其他用途 逐一人工審查所有合併藥物與補充品，特別是可能影響 CYP3A 或 P-glycoprotein 的藥物，並確認肝腎功能與既往毒性 建立個體化的臨床、血液、肝腎、肌肉與尿液監測及急症轉介計畫；不得從個案或人用標示自動產生門檻
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。
20 minutes
fecal