商品名:Acthar
Corticotropin (ACTH). Corticotropin is a natural peptide hormone, composed of 39 amino acids. The formulation is prepared into a gel for injection. It stimulates normal synthesis of cortisol and other hormones from adrenal cortex.
ACTH is used for diagnostic purposes to evaluate adrenal gland function. Another closely related synthetic product, cosyntropin, is used for the same purpose. The availability of Acthar gel has been limited, and cosyntropin is often used as a substitute. Compounded formulations may not be equivalent.
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
確認是 corticotropin 或 repository ACTH,而非 cosyntropin、tetracosactide、內生性 ACTH 檢驗或 corticotropin-releasing hormone 確認精確商品、法域、現行標示、供貨、來源、劑型、濃度、USP 效價單位、批號、保存與效期 將犬診斷、犬貓歷史治療標示、貓科研究、馬或鳥類 compounding nomination 與人體慢性治療完全分開 確認診斷問題、近期藥物、基礎檢體、刺激後檢體、採樣時點、assay、實驗室 cutoff 與判讀限制 院內備妥急性反應處置與觀察能力,且不得把人體長期治療不良反應頻率轉成獸醫單次暴露頻率 完成 exact bilateral interaction review;class-only、assay-only 或人用標示不得直接建立自動 pair
DRUGAPI 劑量審查引用的獸醫官方標示(各標示只適用於其產品、物種與法域,不可互換)
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。