商品名：HydroDiuril and generic
Thiazide diuretic. Like other thiazide diuretics, it inhibits sodium reabsorption in distal renal tubules and causes urinary diuresis. Because thiazide diuretics act in the distal tubules (at the point where most water has already been reabsorbed), their diuretic effects are not as great as compared to loop diuretics such as furosemide.
Like other thiazide diuretics, hydrochlorothiazide is used to increase excretion of sodium, potassium, and water. It also has been used as an antihypertensive. Because thiazide diuretics decrease renal excretion of calcium, they also have been used to treat uroliths containing calcium (calcium oxylate uroliths). Use in animals has been primarily derived from anecdotal experience. There are no well-controlled clinical studies or efficacy trials to document clinical effectiveness.
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
確認診斷、治療目標與替代方案 確認精確產品、成分型態與監管狀態 分開判讀犬、貓與牛的疾病證據 評估體液、血壓、腎肝功能、電解質與酸鹼狀態 核對過敏病史、併用利尿劑及所有潛在腎臟與血壓風險藥物 建立疾病專屬追蹤與停止條件
DRUGAPI 劑量審查引用的獸醫官方標示（各標示只適用於其產品、物種與法域，不可互換）
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。
65-75%