商品名:Kinidin Durules*, Quinidine sulphate*
An antiarrhythmic drug (class Ia with some class III actions) which decreases myocardial excitability and contractility, slows conduction velocity and prolongs refractory period in the atria, ventricles and His-Purkinje system. It is also an alpha- adrenoreceptor antagonist and may therefore also cause hypotension and peripheral vasodilation.
Rarely used. Management of rapid or haemodynamically significant ventricular arrhythmias such as frequent, complex ventricular premature complexes or ventricular tachycardia. May be useful for some supraventricular arrhythmias, such as bypass tract- mediated supraventricular tachycardia and for cardioversion of acute atrial fibrillation in dogs. Patients exhibiting signs of toxicity or a lack of response should have their serum levels measured. Serum therapeutic levels are 0.0025–0.005 mg/ml in
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
不同 quinidine 鹽、base equivalent、IR/ER、物種、route 與 AF 轉復方案不能合併;貓公開來源明確不應使用,馬需連續監測與累積/毒性停藥條件。
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。